The traditional classification of multiple sclerosis (MS) into distinct subtypes – relapsing-remitting, primary progressive, and secondary progressive – has been challenged by consistent evidence of early and continuous neurodegeneration in MS [1]. A diffuse relentless smouldering disease activity affects the whole central nervous system (CNS) leading to a gradual accumulation of disability [2]. The term … Continue reading Neurodegeneration in MS: A race against time